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91.
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Frank Roschangar Jianxiu Liu Marine Dufour Vittorio Farina Azad Hossain Heewon Lee Richard Varsolona Pierre Beaulieu Chris H. Senanayake 《Tetrahedron letters》2008,49(2):363-366
A regioselective Larock approach to 3-substituted-2-pyridin-2-ylindoles from 2-alkynylpyridines and 2-iodoanilines is described herein. The unexpectedly high regioselectivity can be rationalized by a combination of steric, coordinative and electronic effects. 相似文献
94.
Hassan Azad 《Bulletin des Sciences Mathématiques》2009,133(4):330-334
Let KC be the complexification of a compact connected Lie group K. Fixing a K-invariant inner product on Lie(K), the total space of T∗K is identified with KC. We show that the Liouville symplectic form on T∗K is Kähler with respect to the complex structure of KC. 相似文献
95.
96.
Alireza Banaei Afshin Saadat Mina Mohammad Goli Patrick McArdle Eslam Pourbasheer Parinaz Pargolghasemi 《Heteroatom Chemistry》2016,27(6):353-360
Two novel dithiophosphonate ligands, HS2P(p‐C6H4OMe)(OCH2CH2CH(CH3)2) ( 1 ) and HS2P(p‐C6H4OMe)(OCH(CH3)2) ( 2 ), were synthesized and characterized by multinuclear (1H, 31P, and 13C) NMR, infrared spectroscopy as well as elemental analysis. The reactions of 1 and 2 with NiCl2·6H2O and Cd(NO3)2·4H2O in methanol led to novel complexes 3 and 4 . The single crystal X‐ray structures of 3 and 4 showed tetracoordinated structure with square planar geometry for the nickel complex, while it showed pentacoordinated structure with distorted square‐pyramid environment for the cadmium complex. 相似文献
97.
Hassan Y. Aboul-Enein Garshasb Rigi Mohsen Farhadpour Alireza Ghasempour Gholamreza Ahmadian 《Chromatographia》2017,80(11):1633-1639
Staphylococcal protein A (protein A) is an important protein frequently used in research studies within the fields of biomedicine and biotechnology. Due to some limitations in available protein purification methods which can hold the native structure of the protein A without changing the folding or adding histidine to structure of this protein, its separation in the native form is difficult. In this study, a new cost-effective and powerful technique was introduced for separation of the full-length and truncated forms of recombinant protein A, without any alteration in their 3D structures. Per aqueous liquid chromatography with bare silica gel stationary phase and water:acetonitrile as the mobile phase was proved to be an attractive choice among the range of separation methods. Similar to hydrophilic liquid chromatography, this method employs high percentage of water in mobile phase. The effects of mobile phase composition, pH, and salt concentration on the retention behavior of protein A on bare silica gel stationary phases were investigated. In this method, applying high amounts of aqueous solvent accompanied by a minimum percentage of organic solvent could successfully separate protein A with preservation of folding, and any affinity-tagged group such as histidine has not occurred on its structure. Purity of the fractions obtained by the proposed method was confirmed using SDS-PAGE, western blotting, and matrix-assisted laser desorption ionization time-of-flight mass spectrometry. According to the results of ELISA, separated proteins retained their ability of binding to antibody. 相似文献
98.
合成了纳米尺度氧化石墨烯(NGO)层,用作碳催化剂高效催化苄醇与芳香醛的氧化反应.对于醇氧化反应,当80℃时H2O2存在下,NGOs(20 wt%)可高效催化醇选择性生成醛,其反应速率和产率取决于醇上取代基的性质.对于4-硝基苄醇,反应24 h后,只有10%可转换为相应羧酸.相反,4-甲氧基苄醇和二苯基甲醇分别反应仅9和3h则可完全转化为对应的羧酸和酮.NGO碳催化剂上芳香醛氧化速率高于醇氧化速率.对于所有的醛,采用7 wt% NGO作催化剂,在70℃反应2-3 h后,就可完全转化为相应羧酸.我们讨论了NGO催化剂结构对苄醇和芳香醛氧化反应影响的可能机理. 相似文献
99.
Hamid Beyzaei Mohammadreza Moghaddam-Manesh Reza Aryan Behzad Ghasemi Alireza Samzadeh-Kermani 《Chemical Papers》2017,71(9):1685-1691
Pyrazolo[3,4-d]pyrimidines are one of the most important classes of fused heterocyclic compounds which exhibit a broad range of biological and medicinal properties. They are known as anticancer, antifungal, antibacterial, antiviral and anti-inflammatory agents. In this study, some new 6-substituted 4-amino-pyrazolo[3,4-d]pyrimidine derivatives were prepared via reaction of 5-amino-3-methyl-1-phenyl-1H-pyrazole-4-carbonitrile with various nitriles in the presence of sodium ethoxide as catalyst. The inhibitory properties of synthesized compounds were studied according to CLSI guidelines against some pathogenic bacteria including four gram-positive strains (Streptococcus pyogenes, Staphylococcus aureus, Bacillus cereus and Bacillus subtilis subsp. spizizenii) and three gram-negative strains (Pseudomonas aeruginosa, Shigella flexneri and Salmonella enterica subsp. enterica). The antibacterial effects of all derivatives were compared with those of antibiotics belonging to different classes. The values were reported as inhibition zone diameter (IZD), minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The effect of substituents on the biological activity of derivatives was discussed as well. The inhibitory effect of compound 6a, was shown to be the most, with MIC values in the range of 32–4096 μg/mL. Since most of the synthesized compounds were effective against Streptococcus pyogenes and Pseudomonas aeruginosa, they can be considered as inhibitors of these two bacteria. 相似文献
100.
N,N′‐Diiodo‐N,N′‐1,2‐ethandiylbis(p‐toluene sulfonamide) (NIBTS) is a good and new reagent for synthesis of 2‐arylbenzimidazoles and 2‐arylbenzothiazoles at room temperature under solvent‐free condition with good to high yield. Absence of solvent, short reaction times, non‐corrosive, operational simplicity and environmentally friendliness are the main advantages of this procedure. 相似文献